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Quantum SI

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History

Quantum-Si Incorporated, a pioneering company in the field of proteomics, has a rich history dating back to its founding in 2013. This section explores the company s origins, mission, key milestones, and leadership.

Founding

Quantum-Si was founded by Dr. Jonathan M. Rothberg, Ph.D., who currently serves as the company s Executive Chairman. Dr. Rothberg s vision was to make protein sequencing accessible to the proteomics and multiomics community, building on his previous success in democratizing next-generation sequencing technology at Ion Torrent.

Mission and Focus

The company s mission is to combine advanced technology, data science, and human ingenuity to develop solutions that address some of the world s most pressing challenges. Quantum-Si s primary focus is on revolutionizing the field of proteomics through the development of next-generation protein sequencing technologies. Their flagship product, Platinum®, is the world s first next-generation single-molecule protein sequencing platform, utilizing proprietary recognizers to identify proteins and amino acids through kinetic binding signatures.

Key Milestones

  • Development of Platinum®: Quantum-Si introduced Platinum®, a groundbreaking protein sequencing instrument designed to make proteomic research accessible to every lab. This innovative technology integrates biology, chemistry, artificial intelligence, and semiconductor technology to enable unprecedented scale and precision in protein analysis.
  • New Headquarters: In 2023, Quantum-Si unveiled a new headquarters in Branford, Connecticut, featuring world-class laboratory and office space to support the scaling of their operational and development capabilities.
  • Global Expansion: In January 2024, Quantum-Si announced a partnership with TOMY Digital Biology Co., Ltd. to distribute their Platinum® protein sequencing instrument in Japan, expanding their reach into the Japanese scientific community.

Leadership

Quantum-Si is led by a team of experienced executives, including:

  • Dr. Jonathan M. Rothberg, Ph.D. (Founder & Executive Chairman)
  • Jeffrey Alan Hawkins (CEO & Director)
  • Dr. Patrick Schneider, Ph.D. (President & COO)
  • Claudia Napal Drayton (Chief Financial Officer)
  • Dr. Christian Lapointe, J.D., Ph.D. (General Counsel & Corporate Secretary) Quantum-Si has established itself as a leader in the proteomics industry through its innovative technology and commitment to advancing scientific research and drug development. The company s focus on making protein sequencing more accessible and precise has positioned it at the forefront of the next generation of proteomics research tools.

Products & Solutions

Quantum-Si, known as The Protein Sequencing Company™, has introduced innovative products revolutionizing the field of proteomics.

Platinum® Pro

The flagship product, Platinum® Pro, is a next-generation benchtop protein sequencer offering:

  • Streamlined User Experience: An enlarged touchscreen with an intuitive interface for various applications including proteoform analysis and protein barcoding.
  • Flexible Data Analysis: Options for local or cloud-based data analysis, suitable for diverse research environments.
  • Pro Mode: Enables custom application development through a Technology Access Program, fostering biopharmaceutical innovation.
  • Integrated Workflow: A comprehensive system simplifying complex protein sequencing for widespread lab accessibility.

Protein Barcoding Kit

This kit complements the Platinum® Pro, designed for multiplexed protein screening:

  • Utilizes peptide barcodes for efficient protein screening in biopharma research.
  • Supports critical applications such as LNP delivery optimization, mRNA therapeutics evaluation, and protein characteristic analysis.
  • Reduces time and costs with a streamlined workflow, detecting low-abundance proteins in under an hour of hands-on time.

Key Innovations and Benefits

  • Accessibility: Both products democratize proteomics access, simplifying complex processes for a wider range of researchers.
  • Distribution: Partnership with Avantor expands Platinum Pro availability in the U.S. and Canada.
  • Advanced Capabilities: Built on the original Platinum system's foundation, these products advance proteomic research, drug discovery, and diagnostics beyond existing tools. Quantum-Si's products aim to revolutionize proteomics by providing powerful, user-friendly, and versatile tools for protein sequencing and analysis, pushing the boundaries of life science research and applications.

Industry Peers

Quantum-Si Incorporated, a pioneer in next-generation protein sequencing, operates within the competitive Life Sciences Tools and Services industry. Key industry peers and competitors include:

Major Competitors

  1. Thermo Fisher Scientific: A leading provider of analytical instruments, reagents, and software for protein sequencing and analysis, commanding a significant market share.
  2. Illumina: Renowned for high-throughput sequencing platforms used in genomics research and protein sequencing through mass spectrometry-based technologies.
  3. Agilent Technologies: Offers a range of analytical instruments and solutions competing directly with Quantum-Si's offerings.
  4. Danaher Corporation: A diversified science and technology company with several life sciences brands, presenting significant competition.

Other Notable Peers

  • Codexis, Inc.: Specializes in enzyme engineering and manufacturing.
  • Personalis, Inc.: Focuses on advanced genomics for cancer and immune system diseases.
  • ChromaDex Corporation: Develops nutraceutical products and life sciences tools.
  • OmniAb, Inc.: Specializes in antibody discovery.
  • Nautilus Biotechnology Inc., Quanterix Corporation, and SomaLogic Inc.: Each offers specialized technologies and solutions in the life sciences tools and services industry. These companies compete with Quantum-Si in various aspects of life sciences research, diagnostics, and tool development. The diversity of competitors highlights the dynamic and innovative nature of the industry, driving continuous advancements in protein sequencing and analysis technologies. The competitive landscape pushes companies like Quantum-Si to continuously innovate and improve their offerings, ultimately benefiting the broader scientific community and advancing the field of proteomics.

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